Dab tsi yog qhov cuam tshuam ntawm 5-HTP?

5htp uayog ib qho compound uas tsim los ntawm kev tawg ntawm tryptophan. Tryptophan yog ib qho amino acid uas muaj nyob hauv ntau cov khoom noj muaj protein ntau, suav nrog nqaij qaib, qe, nqaij liab, lentils, thiab taum.

Ib zaug hauv lub hlwb, hloov mus rau serotonin. Serotonin feem ntau hu ua "kev txaus siab neurotransmitter" vim tias nws muaj nyob rau lub sijhawm muaj kev xav zoo, xws li kev zoo siab.

Kuj tseem metabolizes rau cov tshuaj hormone melatonin, uas pab tswj kev pw tsaug zog thiab tswj kom zoo circadian rhythms (pw tsaug zog / tsaug zog)

Hauv Tebchaws Meskas, Canada, thiab lwm lub tebchaws thoob ntiaj teb, 5-HTP yog muag raws li kev noj zaub mov noj uas tau noj los ntawm cov noob ntawm Griffonia simplicifolia cog. Hauv cov tshuaj African hauv paus txawm, Griffonia noob extract, hmoov, thiab tshuaj yej yog ib txwm siv rau cov kev xav tsis zoo thiab cov kab mob me feem ntau.

Ib qho laj thawj tseem ceeb uas tib neeg siv 5-HTP yog rau kev nyuaj siab. Nws tau raug ntsuas los ntawm Lub Tsev Kho Mob Ntuj Cov Ntaub Ntawv raws li Muaj Peev Xwm Zoo hauv kev txhim kho cov tsos mob ntawm kev nyuaj siab.

Fibromyalgia yog ib qho mob uas xav tias yuav cuam tshuam nrog qis qis ntawm serotonin hauv lub cev. Fibromyalgia yog tus cwj pwm los ntawm qhov mob musculoskeletal, kev ntxhov siab, kev nyuaj siab thaum sawv ntxov, thiab insomnia (feem ntau vim qhov mob). Cov kev tshawb fawb soj ntsuam ua ntej tau pom tias noj 100 mg 5-HTP peb zaug ib hnub ua rau cov tsos mob fibromyalgia.

5-HTP kuj tseem siv los ua cov tshuaj tiv thaiv kev qab los noj mov thiab txhawb nqa raws li cov khoom hnyav. Kev tshawb fawb tau pom tias cov qib siab ntawm Serotonin tuaj yeem muaj kev noj qab haus huv suppressant nyhuv.

5-HTP Ntxiv Kev Nyab Xeeb thiab Kev Siv Tshuaj

5-HTP tau raug ntsuas los ntawm Natural Medicines Database li Possibly Safe rau kev siv qhov ncauj rau cov neeg laus. Nws yuav tsum tsis txhob siv los ntawm cov poj niam cev xeeb tub thiab pub niam mis, thiab kev siv rau hauv cov xwm txheej no suav tias yog Tsis Muaj Kev Nyab Xeeb.

5-HTP cov tshuaj yog siv rau ntau yam mob thiab rau ntau yam kev txhawb nqa kev noj qab haus huv. Cov kev siv no yuav xav tau ntau npaum li cas. Kev noj tshuaj kuj tseem nyob ntawm tus kheej xav tau, rhiab heev, biochemical pleev, hnub nyoog, qhov hnyav, thiab lwm yam.

Paub txog kev noj tshuaj kom raug rau koj yog qhov tseem ceeb rau kev tiv thaiv lossis tshem tawm cov kev pheej hmoo ntawm kev phiv. Hauv qab no yog qee cov kev mob tshwm sim, uas tuaj yeem tshwm sim, nrog rau kev cuam tshuam tshuaj thiab contraindications.

kev mob plab hnyuv

Cov teeb meem hauv plab hnyuv yuav tshwm sim thaum noj 5-HTP vim muaj qib serotonin siab. 5-HTP nce serotonin synthesis nyob rau hauv lub hlwb tab sis kuj tuaj yeem metabolized rau hauv serotonin hauv plab. Kev mob plab me me yog qhov tshwm sim ntau tshaj 5 -HTP cov kev mob tshwm sim los ntawm cov neeg siv.

Raws li ib txwm muaj, thaum cov zaub mov nkag mus rau hauv lub plab zom mov, serotonin raug tso tawm los ntawm cov hlwb ntawm lub plab thiab cov hnyuv. Qhov no tso tawm serotonin ua rau lub plab hnyuv phab ntsa cog lus. Qhov no yog ib qho txheej txheem hu ua peristalsis, thiab cov nthwv dej ntawm cov leeg nqaij pab Siv los txav zaub mov los ntawm kev zom zaub mov.

Yog tias cov qib Serotonin dheev nce siab dua li ib txwm, nws yuav ua rau cov leeg mob sib kis ntau dua li niaj zaus. Qhov no yuav ua rau muaj kev phiv xws li mob plab, ntuav, lossis raws plab.

Cov tshuaj feem ntau tsuas yog siv cov tshuaj me me los yog noj 5-HTP ntsiav tshuaj nrog zaub mov, kom cov khoom xyaw metabolized qeeb dua.

5-htp hmoov ntau thiab serotonin syndrome

Ib qho kev mob tshwm sim ntau dhau yog ib qho mob hu ua Serotonin Syndrome. Qhov no feem ntau tsis tshwm sim thaum noj 5-HTP los ntawm nws tus kheej ntawm cov koob tshuaj ib txwm muaj, tab sis nws tuaj yeem tshwm sim thaum noj tshuaj ntau heev, lossis ua ke nrog qee yam tshuaj.

5-HTP tau pom tias muaj kev cuam tshuam tsis zoo nrog cov tshuaj tiv thaiv kev ntxhov siab ntawm MAOI (monoamine oxidase inhibitor) lossis SSRI (xaiv serotonin re-inhibitor) chav kawm.

Thaum 5-HTP siv nrog cov tshuaj no, qhov no tuaj yeem ua rau Serotonin Syndrome. Qhov no tshwm sim thaum muaj Serotonin ntau dhau hauv lub cev. Qhov mob hnyav ntawm tus mob no nyob ntawm qhov concentration ntawm Serotonin thiab tuaj yeem muaj los ntawm cov tsos mob me me mus rau qhov ua rau muaj kev phom sij rau lub neej. .

Cov tsos mob yuav tshwm sim sai thiab cuam tshuam rau ntau qhov chaw ntawm lub cev. Hauv qab no yog qee qhov kev phiv tshwm sim:

Mob taub hau

mus do

Mania (lub xeev arousal thiab/los yog hyperactivity)

xav tsis thoob

coma

spasms (tsis yeem twitches ntawm cov leeg)

hyperreflexia (ntau reflexes)

Ntshai

tshee hnyo

tawm hws ntau dhau

kub

Ntshav siab (siab ntshav siab)

Cardiac (ntau lub plawv dhia)

xeev siab

raws plab

Yog tias tsis kho, serotonin syndrome tuaj yeem ua rau tuag taus. Yog tias tam sim no koj tab tom noj tshuaj tiv thaiv kev ntxhov siab lossis lwm yam tshuaj uas cuam tshuam rau kev tsim cov serotonin hauv lub hlwb, tham nrog kws kho mob ua ntej noj 5-HTP los tiv thaiv cov kev mob tshwm sim tseem ceeb heev.

5-htp hmoov muag muag tshuaj sib cuam tshuam

5-HTP tuaj yeem cuam tshuam tsis zoo rau qee yam tshuaj uas tau muab rau cov neeg mob Parkinson. Qhov no suav nrog cov tshuaj carbidopa, tseem hu ua Lodosyn, uas inhibits aromatic L-amino acid decarboxylase. Qhov no yog ib qho enzyme uas koom nrog hauv kev sib txuas ntawm neurotransmitters dopamine thiab serotonin.

Yog tias 5-HTP siv nrog carbidopa, nws yuav ua rau xeev siab, ntuav thiab cov tsos mob zoo li scleroderma (shrinkage lossis hardening ntawm daim tawv nqaij thiab cov ntaub so ntswg sib txuas).

Lwm cov tshuaj uas yuav cuam tshuam tsis zoo rau 5-HTP suav nrog, tab sis tsis txwv rau: lorazepam (cited hauv kab lus no), phenobarbital (Donnatal), yias (Donnatal), pyridoxine (Ambien), hnoos suppressants muaj xuab zeb Fen ( xws li Antitussive), meperidine (Demerol), thiab tramadol (Ultramer).

Kev sab laj tus kheej nrog koj tus kws kho mob txog cov kev mob tshwm sim ntawm 5-HTP thiab txhua yam tshuaj raug pom zoo